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Microbial Genomics Meets Functional Microbiology
The von Mentzer Lab at the University of Gothenburg combines computational biology and experimental microbiology to understand how pathogenic bacteria evolve, adapt to different hosts, and cause disease. Our work integrates large-scale genomic data with laboratory experiments to answer fundamental questions in bacterial evolution and host-pathogen interactions.
Research
Our research focuses on the evolution of pathogenic Escherichia coli, with particular emphasis on bacterial adhesion, plasmid biology, antimicrobial resistance, and host adaptation.
We combine comparative genomics, bioinformatics, machine learning, structural prediction and experimental microbiology to identify new virulence factors and understand how bacterial traits emerge, spread and evolve.
Our goal is to develop openly available datasets, tools and resources that support the wider microbiology community.
Our Team
We are an interdisciplinary team bringing together microbiologists, bioinformaticians and computational biologists. Our projects span bacterial genomics, functional microbiology and One Health, and are carried out through collaborations across Europe, Asia and Africa.
We welcome students and researchers from diverse backgrounds who enjoy combining computational and experimental approaches.